Upon starting your game of Resident Evil 2, you'll be asked which character you'd like to play as - rookie cop Leon S. Kennedy or obscenely capable college student Claire Redfield. Seeing the campaign through as either one or the other, you'll be meeting unique characters, fighting different enemies and wielding specialist weapons. Upon completing that campaign, you'll be prompted to begin a New Game '2nd Run,' a follow-up scenario featuring the other character where the ending and certain parts of the game have been changed. It's only after completing this second run that you'll get the 'true ending' of the game, and after this second play through you'll also unlock The Fourth Survivor mode and the 2nd Run scenario for your first character.